Abstract: As an important regional central city in the upper reaches of the Yangtze River, Yibin has actively promoted industry-city integration in recent years under the philosophy of "developing cities to attract industries and using industries to attract people," achieving a trans formative shift from "one black, one white" to "one blue, one green." In 2024, its GDP exceeded 400 billion yuan, with emerging industries such as power batteries and crystalline silicon photovoltaic rising rapidly; the built-up area of the central urban district reached 189.7 square kilometers, with a permanent resident population of 1.788 million. However, in the transition from "rapid expansion" to "deep integration," Yibin still faces structural challenges, including mismatches in spatial organization and functional layout, shortcomings in public services and infrastructure, bottlenecks in industrial support and talent recruitment and development, constraints related to ecological conservation and green development, and obstacles to institutional mechanisms and policy coordination. Based on a systematic review of the current status and measurement analysis of industry-city integration in Yibin, this paper conducts an in-depth analysis of the above five aspects of issues and proposes corresponding pathways and strategies: building a spatial development pattern featuring clustered collaboration and work-life balance; promoting the decentralization of public services such as education and healthcare to the grassroots level; establishing an innovation value chain integrating industry, academia, research, and application, and bridging talent and industry; strengthening the green and low-carbon ecological security barrier in the upper Yangtze River; and improving a governance system that combines centralized and decentralized management with clear rights and responsibilities, with the aim of providing a reference for similar cities in empowering high-quality development through deep integration of industry and urban development.